Calming pipettes x3u The Calming Spot On pipettes for dogs calm and reduce behavioral problems in dogs of all breeds and ages in a natural and effective way. They contain valerian extract and a weekly application will suffice to avoid problems with furniture scratches, urine and smell marks in the home, excessive barking or boisterous behavior. How to administer: Apply a pipette between the ears, once a week. The valerian extract will be activated 1 hour after the pipette is applied. In case you bathe the dog, reapply the drops or their effect may be diminished.